ABSTRACT
The present study was designed to evaluate the effect of some antidiabetic plants on the hematological parameters in aloxan induced diabetes in albino rats
Eighty adult albino rats [120- +/- 20 gm b.wt] were randomly divided into eight groups ten on each group, the first group conserved as control group. The remaining rats were injected with alloxan to induce diabetes. The second group conserved as diabetic group. The third group was diabetic rats treated with a mixture consists of Nigella Sativa, Aloe Vera, Ferula assa-foetida , Boswelli Carteri, Commiphora Myrrha. [0.1ml/100gm b.wt]
Fourth group treated with 0.1ml/100gm b.w of Nigella Sativa, Fifth group treated with 0.05ml/100gm b.w of Aloe Vera,Sixth group treated with 0.1ml/100gm b.w of Ferula assa-foetida, Seventh group treated with 0.1ml/100gm b.w of Boswelli Carteri, Eighth group treated with 0.1ml/100gm b.w of Commiphora Myrrha. Haematological parameters includes: red blood cell count [RBCs], hemoglobin concentration [Hb], hematocrit value [Hct%], total and differential white blood cell cont [WBCs] were done after 30 days of treatment and after 15 days of recovery period
The result of RBCs count, Hb concentration and Hct value were significantly decreased in diabetic, Nigella Sativa and Aloe Vera treated groups, throughout the experiment, except Aloe Vera treated group showed insignificant change after the recovery period.while insignificant changes was recorded in the remnant groups during the experimental period
WBCs count, lymphocyte and neutrophil percentage were highly significant increased in diabetic and Ferula assa-foetida treated rats after treatment and recovery periods. While insignificant differences were observed in the other treated groups. Moreover, no significant changes were recorded in eosinophils and monocytes in all groups throughout the study period
Diabetes mellitus in experimental animal can be treated with some plants which have antidiabetic effect, the present investigation was designed to illustrate any hazard effect of these plants on some hematological parameter. Further investigations on each plant and their mixture are needed to role out its effect on both diabetes and the vital parameters